First proof of concept of CPPF
08 aug 2015

First proof of concept of CPPF

Before starting up Randomized Clinical Trials (RCT)

08 aug 2015

Before starting up Randomized Clinical Trials (RCT) we performed a Safety & Feasibility study on the CPPF method. In an experimental and highly controlled setting 21 patients underwent the Continuous Pericardial Flushing Method adjacent to their cardiac surgical procedure. Most important conclusions were that the CPPF method was safe and feasible in this experimental setting. No method related complications were observed. In comparison with a historic group of patients, the CPPF patients showed a 30% reduction in blood loss but this finding needs to be confirmed in a RCT. The full article can be read and PDF free download at; http://www.ebiomedicine.com/article/S2352-3964(15)30083-9/abstract.

David R. Koolbergen

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